The liver generates bile and holds a substance known as bilirubin. Bile moves from the liver to the intestine. If there's a tumor-related issue in this region, it can impede the flow of bile.
This can occur with periampullary cancer, pancreatic head cancer, uncinate process cancer, or terminal bile duct cancer.
The blockage leads to higher pressure in the biliary system, causing bilirubin to be absorbed into the bloodstream and then deposited in the whites of the eyes or the skin.
And this is how jaundice develops in cases of pancreatic cancer.
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